Dr. CI: labo (Japanese: Co., Ltd. ドクタシラボボシラボ) is the world's first medical beauty and skin care brand. To the skin care products specially developed for problem skin, it was founded in February 1999 by Mr. Great Wall Noguchi, a medical doctor, dermatologist and head office of Chengye clinic. At first, it only sold six skin care products such as marine collagen moisturizing water gel through mail order.